PS-5 inhibition of a .BETA.-lactamase from Proteus vulgaris.
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چکیده
منابع مشابه
The Journal of Antibiotics Ps-5 Inhibition of a B-lactamase from Proteus Vulgaris*
Inhibition of Proteus vulgaris B-lactamase by a new B-lactam antibiotic, PS-5 was studied kinetically. There were two stages of inhibition. In the early stage, PS-5 inhibited the Blactamase by formation of a MICHAELIS-complex, and showed a competitive inhibition pattern with Kj-value of 0.22 uM (substrate, cephaloridine). After the formation of a MICHAELIScomplex between PS-5 and the enzyme, PS...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1980
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.33.293